NIAID Director Anthony Fauci discusses recent developments in the global COVID-19 pandemic with JAMA Editor Howard Bauchner. Recorded on June 2, 2020.
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Topics discussed in this intervew:
0:00 Introduction
0:32 Phase 3 trials for a coronavirus vaccine will start July. Could you talk a little bit about what that will look like?
2:12 The Moderna, phase 2 trial, how large is that, and what will be learned from the phase 2 before we get to the phase 3 in July?
2:36 How long does a phase 3 trial need to last to know if there's effectiveness?
3:40 Will there be age, sex, race, ethnicity, diversity amongst the 30,000 trial participants, or will it be focused on healthy, younger individuals?
4:08 Are you optimistic based on the acceleration in vaccine development over the past few years and how quickly we've been able to get to phase 3 trials?
6:05 What happens with the production of that candidate vaccine? Will there be enough doses available in the fall?
7:50 Can you see a role for monoclonal antibodies, as we try to sort out schools and colleges, protecting the elderly, and nursing home residents?
8:58 Will there be a sufficient amount of convalescent plasma available?
9:24 Vitamin D and whether or not it could be helpful in treatment of COVID-19.
11:07 Zinc and azithromycin
12:21 Do you have a sense of what's happening in the states that have opened up early?
14:15 Immunity passports
15:14 Opening schools safely in the fall.
17:14 Asymptomatic spread
18:55 IgG and IgM antibodies
20:23 Remembering AIDS activist Larry Kramer
25:55 Your equanimity. Does it come from your parents? Does it come from your Jesuit education? It's extraordinary under the face of just remarkable and unfair criticisms.